| abstract |
Provided is a drug comprising a compound having a CRF antagonistic action as an active ingredient in the prevention and / or treatment of a neuropsychiatric disorder or a peripheral organ disease. Formula (I) (In the formula, R 1 represents an optionally substituted C3-10 branched alkyl group, etc., R 2 represents a hydrogen atom or an optionally substituted C1-4 alkyl group, and R 3 is substituted. represents may also be C1~4 alkyl group or a halogen atom optionally, R 4 represents such optionally substituted C1~4 alkyl group, a cyclic group ring1 is having good flatness may have a substituent Or a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug thereof is a CRF antagonistic action in the prevention and / or treatment of a neuropsychiatric disorder or a disease of a peripheral organ. It is useful as a pharmaceutical ingredient having |