abstract |
Formula (I): (In the formula, ring A is a carbocyclic group which may have a substituent or a heterocyclic group which may have a substituent, E is lower alkylene, etc., X is S, O Or NR 1 , R 1 is hydrogen or lower alkyl, R 2a , R 2b , R 3a , R 3b , R 4a and R 4b are each independently hydrogen, halogen, hydroxy, etc. n and m Each independently represents an integer of 0 to 3, n + m is 1 to 3, and R 5 is hydrogen, lower alkyl optionally having substituent (s), etc.) Or a pharmaceutically acceptable salt thereof, or a solvate thereof, as a pharmaceutical composition for treating Alzheimer's disease. |