abstract |
Provision of a preparation exhibiting good dissolution properties in a wide pH range. (A) N 1- (5-chloropyridin-2-yl) -N 2 -((1S, 2R, 4S) -4-[(dimethylamino) carbonyl]-represented by the following formula (1) 2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo [5,4-c] pyridin-2-yl) carbonyl] amino} cyclohexyl) ethanediamide, a pharmacologically acceptable salt thereof, or A pharmaceutical composition comprising these hydrates and (B) one or more selected from sugar alcohols and water-swellable additives. |