abstract |
As this invention, the compound (henceforth this invention compound) represented by the following general formula [1] or its pharmaceutically acceptable salt can be mentioned, for example. [Chemical 1] In the general formula [1], one of X and Y represents CH and the other represents oxygen or sulfur, R represents hydrogen or the like, Z represents hydrogen or the like, Ar represents phenyl or the like, and n represents 1 or 2 , M represents 1 or 2, respectively. However, a compound in which n is 2 and m is 2 is excluded. Further, the pharmaceutical composition containing the compound of the present invention or a pharmaceutically acceptable salt thereof as an active ingredient is depression, panic disorder, anxiety, obsessive compulsive disorder, chronic pain, fibromyalgia, obesity, stress urine It can be used as a preventive or therapeutic agent for incontinence, overactive bladder and the like. |