http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2008099715-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-04 |
| filingDate | 2008-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2008099715-A1 |
| titleOfInvention | Process for producing optically active 2-arylpiperazine derivatives |
| abstract | This application makes it a subject to manufacture the optically active 2-aryl piperazine derivative useful as a synthetic intermediate of a medicine and an agrochemical from a cheap and easily available raw material by the method which can be implemented industrially efficiently. This problem is solved by treating an optically active substituted aminodiol derivative produced from an optically active styrene oxide derivative with a sulfonylating agent in the presence of a base, and subsequently reacting the amine compound to form a 2-arylpiperazine derivative. Can do. In particular, an optically active 1-allyl-2-arylpiperazine derivative can be produced by performing deallylation by acting water in the presence of a transition metal catalyst to produce an optically active 1-unsubstituted-2-arylpiperazine derivative. it can. |
| priorityDate | 2007-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 251.