| abstract |
Disclosed is a compound having an excellent JAK3 inhibitory activity and useful as an active ingredient of a therapeutic or prophylactic agent for various immune diseases including autoimmune diseases, inflammatory diseases, and allergic diseases. [Solution] As a result of studying a novel fused heterocyclic derivative, the present inventors have confirmed that the fused pyridine compound of the present invention has an excellent JAK3 inhibitory action and completed the present invention. That is, since the compound of the present invention has an inhibitory activity against JAK3, diseases caused by unwanted cytokine signaling, such as rejection in living transplants, autoimmune diseases, asthma, atopic dermatitis, rheumatism, psoriasis, It has been confirmed that it is useful as an active ingredient of a therapeutic or prophylactic agent for diseases caused by atherosclerosis or abnormal cytokine signaling, such as cancer and leukemia. |