abstract |
The present invention provides nucleic acids such as microRNAs and microRNA precursors having novel sequences. The nucleic acid of the present invention includes detection of microRNA expression or mutation, cell isolation, suppression of gene expression having a target sequence, screening for a substance that promotes or suppresses the function of microRNA, disease caused by abnormal mast cells, It is useful for diagnosis and treatment of diseases caused by abnormal mesenchymal stem cell proliferation or differentiation, cancers and abnormal cell proliferation, tissue hyperplasia, and the like. |