| abstract |
A sustained-release preparation obtained by molding a granulated product containing a blood coagulation factor Xa inhibitor and a mixture containing two or more hydrophilic polymers, and the sustained-release preparation and blood coagulation factor Xa inhibitor By using a pharmaceutical composition in combination with the immediate-release preparation it contains, blood coagulation factor Xa activity can be controlled over a long period of time, which is excellent in convenience and compliance, for prevention or treatment of thrombosis. Provided are a controlled-release preparation containing a blood coagulation factor Xa inhibitor and a method for producing the same. |