http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2008059800-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-18 |
| filingDate | 2007-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2008059800-A1 |
| titleOfInvention | Novel polyamine derivative compounds |
| abstract | The present invention provides a compound that has a sufficiently high affinity for the NMDA receptor, efficiently inhibits calcium ion influx, has low cytotoxicity, has a low molecular weight, and is expected to have good brain migration. Objective. The present invention provides a compound having the general formula (I), or a pharmacologically acceptable salt thereof. [Chemical 1] [Wherein, X represents R 2 —SO 2 —, wherein R 2 represents an optionally substituted lower alkyl group or phenyl group, and Y represents —R 3 —NH—R 4 —. , -R 5 -NH-R 6 -NH -R 7 -, - R 8 -NH-R 9 -NH-R 10 -NH-R 11 -, and, -R 12 -NH-R 13 -NH -R 14 represents a group selected from the group consisting of —NH—R 15 —, wherein R 3 to R 15 each independently represent a C 3 to C 5 alkylene group, and R 1 is hydrogen or substituted. An optional lower alkyl group is shown. Provided that X is a tosyl group, Y is — (CH 2 ) 3 —NH— (CH 2 ) 4 —NH— (CH 2 ) 3 —, and R 1 is hydrogen. ] |
| priorityDate | 2006-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.