http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2008013257-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate | 2007-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2008013257-A1 |
| titleOfInvention | Monoclonal antibody against soluble LOX-1 |
| abstract | Monoclonal antibodies that specifically recognize human soluble LOX-1 are provided, particularly monoclonal antibodies that have a dissociation constant (Kd) of 1 × 10 −9 (M) or less with human soluble LOX-1. The antibody can be produced from a hybridoma prepared by a method comprising the following steps: (1) immunizing a non-human animal with a prokaryotic human LOX-1 extracellular domain, (2) the animal A step of recovering antibody-producing cells from (3) a step of fusing the antibody-producing cells and myeloma cells, and (4) a reaction with the human LOX-1 extracellular domain from among the fused cells obtained in the above step. Selecting a hybridoma producing a monoclonal antibody to be performed, and (5) selecting a hybridoma producing a monoclonal antibody that reacts with a human LOX-1 extracellular domain derived from a eukaryotic cell from the selected hybridomas. |
| priorityDate | 2006-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 123.