| abstract |
The following formula (I) useful for the treatment of diseases such as rheumatoid arthritis and ulcerative colitis having an excellent p38 MAP kinase inhibitory action and reduced side effects: In the formula, R 1 and R 2 each represent a hydrogen atom, a lower alkyl group, an amino group, etc .; R 3 represents a substituted or unsubstituted aryl group or heteroaryl group; R 4 represents a hydrogen atom or a lower alkyl group; R 5 represents a substituted or unsubstituted phenyl group, furyl group or the like; Y represents —CH 2 —, —CO—, —O—, —NH— or the like, Or an pharmaceutically acceptable salt thereof. |