| abstract |
Formula (I) [Wherein, X is a hydrogen atom or a C 1-6 alkyl group, Y is a C 1-6 alkylene group, or —O— (CH 2 ) n — (n represents an integer of 1 to 5); Z is —CONHR A or —NHCONHR B (Where n is not 1 when Z represents —NHCONHR B ). However, R A is a C 1-6 alkyl group substituted with 1 to 3 groups selected from the group consisting of a hydroxyl group and —CONH 2 ; R B represents a hydrogen atom, or a C 1-6 alkyl group substituted with 1 to 3 groups selected from the group consisting of a hydroxyl group and —CONH 2 ]]-C-phenyl 1-thioglucitol The compound or a pharmaceutically acceptable salt thereof or a hydrate thereof inhibits SGLT1 activity and suppresses the absorption of glucose or the like, or inhibits both SGLT1 and SGLT2 activities to inhibit glucose, etc. It is useful as an agent for the prevention or treatment of diabetes due to the urinary glucose excretion action in addition to the suppression of the absorption of urine. |