http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2007097447-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-167 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 |
| filingDate | 2007-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2007097447-A1 |
| titleOfInvention | Nucleic acid protecting group removal method |
| abstract | An object of the present invention is to provide a ribose 3′-ribose derivative in which the 2′-hydroxyl group of ribose is protected with the following substituent (I) and the 3′-hydroxyl group and the 5′-hydroxyl group are protected with a silicon-protecting group. An object of the present invention is to provide a method for efficiently removing a silicon substituent protecting a hydroxyl group and a 5′-position hydroxyl group in a large amount at a low cost. In formula (I), WG 1 represents an electron-withdrawing group. To the ribonucleic acid derivative represented by the following general formula (1), a salt of a tertiary amine and hydrofluoric acid represented by the following general formula (2) or a tertiary amine and hydrofluoric acid A ribonucleic acid derivative represented by the following general formula (3) is produced by allowing the mixture to act and eliminating the silicon substituent protecting the 3′-position hydroxyl group and the 5′-position hydroxyl group of ribose. |
| priorityDate | 2006-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 239.