abstract |
It has been found that cells in which the brain migratory polypeptide is expressed in the cell surface layer pass through the blood-brain barrier and have a translocation activity to the brain. By introducing a desired compound into the brain migratory cells, the compound can be transferred into the brain. For example, by intravenously administering brain migratory cells into which a drug having a therapeutic effect on brain disease is introduced, it can be efficiently delivered into the brain, and effective treatment for brain disease can be performed. Is possible. |