abstract |
The following general formula (II), (Wherein W 3 represents a nitrogen atom or CH, Z 1 represents an oxygen atom or a sulfur atom, R 11 and R 12 represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an alkyl group having 1 to 8 carbon atoms substituted with a halogen atom, or the like, R 13 and R 14 represent a hydrogen atom or an alkyl group having 1 to 8 carbon atoms, A 1 represents an optionally substituted pyrazole or thiophene, And m represents the integer of 2-4. ) Or a salt thereof is used as an activator of PPARδ. |