http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2006118085-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2006-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2006118085-A1 |
| titleOfInvention | Hepatocyte replication promoter and insulin resistance improver |
| abstract | An object of the present invention is to provide a drug and method for promoting replication of hepatocytes, and to provide a drug and method for improving insulin resistance. An effective amount of a neutralizing agent for CXCL10 belonging to a subfamily of chemokines, which are heparin-binding proteins, is administered to hepatocytes to promote hepatocyte replication. As the neutralizing agent for CXCL10, a factor that specifically binds to CXCL10 and suppresses the activity of CXCL10 or a factor that suppresses the expression of CXCL10 is preferably used. The liver tissue can be repaired and regenerated by administering the neutralizing agent to the liver tissue having a disorder. On the other hand, insulin resistance in type 2 diabetes, metabolic syndrome and the like is improved by administering an effective amount of a neutralizing agent for CXCL10 to hepatocytes. |
| priorityDate | 2005-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 453.