abstract |
The present invention relates to an artificial cerebrospinal fluid containing sodium ions 120 to 160 mEq / L, potassium ions 1 to 6 mEq / L, chlorine ions 75 to 155 mEq / L and bicarbonate ions 5 to 45 mEq / L, and further 10 g / L An artificial cerebrospinal fluid containing at least one component selected from the following reducing sugars, 5 mmol / L or less phosphoric acid, 5 mEq / L or less calcium ion and 5 mEq / L or less magnesium ion is provided. The artificial cerebrospinal fluid of the present invention can be used as a lavage or perfusate used in the field of neurosurgery such as intracranial surgery or as a cerebrospinal fluid loss replenisher to prevent or reduce the occurrence of cerebral edema. In addition, cell damage of brain cells can be suppressed. |