abstract |
The present invention relates to acidic salts such as sulfates, hydrochlorides, and methanesulfonates of 4- (1-((4-methylbenzothiophen-3-yl) methyl) benzimidazol-2-ylthio) butanoic acid and its Provide crystals. Further, these benzimidazole derivatives or crystals thereof have chymase inhibitory activity in the living body, and can be used as preventive or therapeutic agents for inflammatory diseases, allergic diseases, respiratory diseases, cardiovascular diseases, or bone / cartilage metabolic diseases. |