| abstract |
Provided are a novel pyrimidine derivative or a pharmaceutically acceptable salt thereof condensed with an aromatic heterocyclic ring selected from thiophene, thiazole and pyridine, and a pharmaceutical composition containing the compound as an active ingredient. These compounds exhibit excellent insulin secretion promoting action and blood glucose elevation inhibiting action. Therefore, pharmaceutical compositions containing these compounds as active ingredients are based on these actions and treat insulin-dependent diabetes (type 1 diabetes), non-insulin-dependent diabetes (type 2 diabetes), insulin resistance diseases and obesity. And / or useful for prevention. |