abstract |
Formula (I) {In the formula, A represents a sulfur atom, an oxygen atom, a formula —SO— or a formula —SO 2 —, R 1 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or the like, and R 2 represents a carbon atom. An alkyl group having 1 to 6 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms and the like, R 3 represents a hydrogen atom and an alkyl group having 1 to 6 carbon atoms, and R 4 represents a hydrogen atom and a carbon atom. R 1 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R 6 represents an alkyl group having 1 to 6 carbon atoms, phenyl, and the like. A group or a substituted phenyl group. } Or a pharmaceutically acceptable salt thereof has a binding inhibitory action between S1P and its receptor, Edg-1 (S1P1), and is useful as a pharmaceutical product. |