| abstract |
Formula (I) [Chemical 1] [Wherein Ar 1 represents a phenyl group which may have 1 to 3 substituents, or an unsubstituted 5- or 6-membered aromatic heterocyclic group; Ar 2 represents (i) an unsubstituted A phenyl group substituted with a lower alkyl group having 1 to 3 groups or atoms selected from a phenyl group, (ii) a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group and a halogen atom, or (iii) a lower alkyl group 5- or 6-membered nitrogen-containing aromatic substituted with 1 to 3 groups or atoms selected from: lower alkynyl group, lower alkanoyl group, carbamoyl group, cyano group, amino group, hydroxyl group, lower alkoxy group and halogen atom X represents a heterocyclic group; X represents a general formula (II) [Chemical 2] (In the formula, the cyclic structure has a lower alkyl group, a carbamoyl group, or a hetero atom selected from a nitrogen atom, an oxygen atom and a sulfur atom in addition to the nitrogen atom described in the above formula, A 4- to 7-membered heterocyclic group optionally substituted with 1 to 4 groups or atoms selected from an amino group, a hydroxyl group, a lower alkoxy group, an oxo group, a lower alkanoyl group, a lower alkylsulfonyl group and a halogen atom; The group represented by this is shown. ] Or a salt thereof or a solvate thereof, and a medicine. |