| abstract |
Phospholipids are mainly used as a liposome preparation with excellent storage stability that can stably carry drugs that impair stability under acidic conditions without losing effects such as blood stability due to membrane modification with hydrophilic polymers. A liposome comprising a unilamellar vesicle formed of a lipid bilayer membrane included as a membrane material, an inner aqueous phase having a pH of 5 or less present in the vesicle, and carrying a drug, the vesicle Provides a liposome preparation in which only the outer surface is modified with a hydrophilic polymer. |