abstract |
We succeeded in isolating bispecific antibodies with alternative ligand function for type I interferon receptor consisting of two types of molecules, AR1 chain and AR2 chain. It also replaces the effects of blood coagulation factor IX / activated blood coagulation factor IX and activated blood coagulation factor VIII, which binds to both blood coagulation factor IX and blood coagulation factor X and enhances the enzyme reaction. A bispecific antibody was successfully produced. |