| abstract |
General formula (1) (In the formula, R 1 represents a hydroxyl group or a carboxyl group, m represents an integer of 1 to 3, R 2 represents an alkyl group or an alkoxy group, n represents an integer of 0 to 4, and ring A represents Represents a 5- to 8-membered saturated or unsaturated nitrogen-containing heterocyclic ring, R 3 represents a haloalkyl group or the like, R 4 and R 5 independently represent a hydrogen atom, a halogen atom, an alkyl group, or the like; Represents methine or nitrogen atom, etc.) Or a pharmaceutically acceptable salt thereof has an antipruritic action and is useful as a therapeutic or prophylactic agent for allergic diseases, skin diseases and the like. |