| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D301-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D301-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-293
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D301-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-30 |
| filingDate |
2004-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2006-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-WO2005007638-A1 |
| titleOfInvention |
Optically active halohydrin derivative and method for producing optically active epoxy alcohol derivative using the same |
| abstract |
An optically active epoxy alcohol derivative useful as a pharmaceutical intermediate is provided by a method that can be carried out simply and industrially safely from inexpensively available raw materials, as well as an important novel intermediate compound halohydrin derivative. Also provided is a process for producing a triazole antifungal intermediate in a short step by reacting a halohydrin with a sulfonamide of triazole. An optically active substituted propionic acid ester derivative is reacted with a haloacetic acid derivative in the presence of a base to form an optically active haloketone derivative, which is then reacted with an aryl metal compound to remove a halohydrin derivative stereoselectively from the substituent on the hydroxyl group. An optically active epoxy alcohol derivative is produced by epoxidation with a base. In addition, a triazole antifungal intermediate is produced in a short process by reacting a halohydrin derivative with a sulfonamide of triazole. |
| priorityDate |
2003-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |