http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2004108924-A1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2004-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2006-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-WO2004108924-A1 |
titleOfInvention | CD9 / CD81 double deficient non-human animal |
abstract | It is an object of the present invention to provide a non-human animal that can be used for drug screening of a therapeutic drug for osteoporosis or a therapeutic drug for chronic obstructive pulmonary disease as a model animal that well expresses the pathology of low-rotation osteoporosis and chronic obstructive pulmonary disease. There is. The present invention comprises a non-human animal characterized in that a gene encoding CD9 and a gene encoding CD81 are deficient in at least somatic cells, and a step of measuring the degree of inhibition of bone formation in the non-human animal. A method of using a human animal as a model animal for osteoporosis and a method of using the human animal as a model animal for chronic obstructive pulmonary disease, comprising the step of measuring the degree of phenotype similar to chronic obstructive pulmonary disease of the non-human animal. is there. |
priorityDate | 2003-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 384.