| abstract |
Formula (I) [Wherein R 1 represents a hydrogen atom, R 2 represents a hydrogen atom, —C (═W) R 6 (wherein W represents an oxygen atom or a sulfur atom, and R 6 represents a substituted or unsubstituted lower group) R 3 represents —C (═Z) R 19 (wherein Z represents an oxygen atom or a sulfur atom, R 19 represents a substituted or unsubstituted lower alkyl or the like), R 4 represents a substituted or unsubstituted lower alkyl or the like, and R 5 represents a substituted or unsubstituted aryl or the like] An M phase kinesin Eg5 inhibitor or the like containing a derivative or a pharmacologically acceptable salt thereof as an active ingredient is provided. |