| abstract |
An object of the present invention is to provide a neuroregenerative drug, a neural stem cell neurogenesis promoting agent, a neuron obtained by culturing neural stem cells in the presence of the neurogenesis promoting agent, and a method for producing the neuron. In order to solve the problem, the present invention provides a nerve regeneration agent containing a substance that inhibits the activity of glycogen synthase kinase-3 as an active ingredient, a neural stem cell neurogenesis promoting agent containing the substance as an active ingredient, Provided are a neuron obtained by culturing neural stem cells in the presence of an agent for promoting neurogenesis, and a method for producing the neuron. The medicament of the present invention is Parkinson's disease, Alzheimer's disease, Down syndrome, cerebrovascular disorder, stroke, spinal cord injury, Huntington's chorea, multiple sclerosis, amyotrophic lateral sclerosis, epilepsy, anxiety disorder, schizophrenia, depression It is useful as a therapeutic agent for neurological diseases such as illness and manic depression. |