| abstract |
Provided is a PDE10A inhibitor useful for the prevention and treatment of Parkinson's disease, Huntington's disease, Alzheimer's disease or schizophrenia. General formula (1) [Wherein, R 1 and R 2 are each independently a hydrogen atom or a lower alkyl group having 1 to 4 carbon atoms, R 3 is a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, or 1 to 3 carbon atoms. Represents a lower alkoxy group. A phosphodiesterase 10A inhibitor comprising a pyrazolo [1,5-a] pyridine derivative represented by formula (I) as an active ingredient is useful for the prevention or treatment of Parkinson's disease, Huntington's disease, Alzheimer's disease or schizophrenia. is there. |