| abstract |
The present invention relates to an isoquinoline compound represented by the following general formula (I) or (II), an optically active form thereof, a pharmaceutically acceptable salt thereof, a water adduct, a hydrate thereof, and a solvate thereof. The present invention relates to a preventive and / or therapeutic agent for diseases caused by enhanced function of poly (ADP-ribose) synthase containing the compound, and a poly (ADP-ribose synthase inhibitor containing the compound In addition, the compound is useful as an agent for preventing and / or treating cerebral infarction, particularly as an agent for preventing and / or treating acute cerebral infarction. |