| abstract |
Provision of a novel amine compound having an effect on diseases such as HIV virus infection, rheumatism or cancer metastasis. An amine compound represented by the following general formula (1). Typically, A 1 and A 2 represent an optionally substituted monocyclic or polycyclic heteroaromatic ring, and W represents a C 3-10 cyclic alkylene group, an optionally substituted monocycle. Or a polycyclic heteroaromatic ring or a monocyclic or polycyclic aromatic ring, a partially saturated polycyclic aromatic ring, and X represents O, CH 2 , C (═O), NR 11 is represented, and D is a group represented by the following formula (4) or (6). Wherein (6), Q is a single bond or represents S, O, and NR 12, Y represents a group represented by the following formula (7). Z represents a monocyclic or polycyclic aromatic ring which may be substituted. Wherein (6), B represents a -NR 25 R 26. R 1 to R 26 in each formula represent a hydrogen atom, an alkyl group, an alkenyl group, or an alkynyl group. |