| abstract |
Because it is a waxy substance, dioctylsodium sulfosuccinate, which is difficult to make into a general colon proximal-release preparation coated with an enteric coating, etc., is released in the upper part of the digestive tract, so it is effective as a direct action It was not right. The present invention has been completed for the purpose of providing a solid preparation having dioctylsodium sulfosuccinate released in the vicinity of the large intestine at the site of action and having an effective armpit effect, and a solution containing dioctylsodium sulfosuccinate Is a solid preparation characterized in that an enteric coating is applied to core particles containing granules obtained by granulating a powder containing light anhydrous silicic acid. |