| abstract |
The differential display method was used to search for genes that differed in expression in eosinophils collected during exacerbation and remission in patients with atopic dermatitis. As a result, the present inventors have succeeded in identifying a NOR-1 (MINOR) gene whose expression is significantly increased in eosinophils in patients in remission with a decrease in eosinophils. The present inventors have found that the gene can be used for screening for allergic diseases and screening for therapeutic drug candidate compounds. |