http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2003104804-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2003-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2003104804-A1 |
| titleOfInvention | Method for searching for substance having antidiabetic action |
| abstract | According to the present invention, [1] a step of measuring a cellular response of a pancreatic β cell when the substance that inhibits the activity of the potassium-ATP channel of the pancreatic β cell is brought into contact with the pancreatic β cell in the presence of the test substance; [2] A step of measuring a cellular response of the cell when the cell is contacted with a substance that inhibits the activity of the potassium-ATP channel of the cell in the absence of the test substance, [3] And a method for searching for a substance having an anti-diabetic action, comprising a step of selecting a test substance that changes the cellular response of the cell, and [1] a test substance and a sulfonyl urea structure under a high glucose concentration Measuring the cellular response of the cell when it is brought into contact with a desensitized pancreatic β cell, [2] measuring the cellular response of the cell under a high glucose concentration, [3] Compare the measured values Method for searching a substance having anti-diabetic activity comprising the step, selecting a substance for changing the cellular response than the test substance. |
| priorityDate | 2002-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 123.