| abstract |
The following formula (I), which is a glycogen phosphorylase inhibitor and is useful as a therapeutic and prophylactic agent for insulin-dependent diabetes (type 1 diabetes), particularly non-insulin-dependent diabetes (type 2 diabetes), insulin resistance diseases, and obesity Of the compound. A glycogen phosphorylase inhibitor, wherein an indole ring or the like is bonded to an A ring (aryl or aromatic heterocycle) via an amide bond, and the A ring has a hydroxyethylene moiety as a substituent. Particularly preferably, the glycogen phosphorylase inhibitor, wherein the ring A has a dihydroxyethylene moiety as a substituent. (Each substituent is as described in claim 1.) |