| abstract |
General formula “Wherein X represents an optionally substituted lower alkylene or alkenylene group; G 1 represents an oxygen atom, sulfur atom or imino group; G 2 represents a carbon atom or nitrogen atom; R a represents hydrogen One or more groups selected from atoms, halogen atoms and optionally substituted alkyl, cycloalkyl and alkoxy groups; R 1 represents an amidino group which may be protected or substituted; R 2 represents a substituted amino group; Or an arylamidine derivative represented by the above or a salt thereof has an excellent antifungal action, has a higher safety, and is useful as an antifungal agent having good pharmacokinetics. is there. |