abstract |
The present invention provides a novel pyrimidine compound having an excellent adenosine receptor (A 1 , A 2A , A 2B receptor) antagonistic action. Specifically, a compound represented by the following formula or a salt thereof, or a solvate thereof is provided. In the formula, R 1 and R 2 are the same or different and each represents a hydrogen atom, a C 1-6 alkyl group which may have a substituent, etc .; R 3 represents a hydrogen atom, a halogen atom, etc .; R 4 represents a substituent. C 6-14 aromatic hydrocarbon cyclic group which may have, 5- to 14-membered non-aromatic heterocyclic group which has at least one unsaturated bond which may have a substituent Etc .; R 5 represents an optionally substituted C 6-14 aromatic hydrocarbon cyclic group or an optionally substituted 5- to 14-membered aromatic heterocyclic group. |