http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2003033468-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 |
| filingDate | 2002-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2003033468-A1 |
| titleOfInvention | Method for producing (S) -α-halomethylpyridine methanol derivative |
| abstract | Provided is a method by which a (S) -α-halomethylpyridine methanol derivative useful as a pharmaceutical intermediate can be easily produced from an inexpensive raw material. By reducing the 2-haloacetylpyridine derivative in an S-selective manner using an enzyme source having the ability to selectively reduce the carbonyl group of the 2-haloacetylpyridine derivative available at low cost, (S) -Α-halomethylpyridine methanol derivative is prepared. Further, by using a hydrohalic acid and an organic solvent from an impurity-mixed (S) -α-halomethyl-3-pyridinemethanol derivative, the halogen of the (S) -α-halomethyl-3-pyridinemethanol derivative is obtained. The hydride is isolated and purified as crystals. |
| priorityDate | 2001-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 206.