abstract |
A substance consisting of a substance that recognizes PD-1, a substance that recognizes a membrane protein present in a cell membrane in which PD-1 is expressed, and a linker. The substance having specificity for PD-1 of the present invention is capable of selectively recognizing PD-1 and a membrane protein present in a cell membrane in which PD-1 is expressed, and transmitting a PD-1 inhibitory signal. It is useful for the treatment and / or prevention of diseases due to immune disorders. |