http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2003004641-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-74 |
| filingDate | 2002-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2003004641-A1 |
| titleOfInvention | Method for producing human thrombin by genetic recombination technology |
| abstract | Provided is a recombinant human thrombin. Human thrombin is cultured 1) A transformant comprising animal cells transformed by an expression vector having a gene encoding prethrombin inserted downstream of the promoter is cultured, and prethrombin is produced and accumulated in the culture medium and collected. 2) a step of activating the collected and collected human prethrombin-containing solution by applying ecarin to convert the solution into human thrombin; and 3) converting purified human thrombin from the reaction solution having undergone the activation step. Efficient production using gene recombination technology including the purification step obtained. It has made it possible to supply a large amount of safe and low-cost human thrombin that has eliminated the involvement of blood-derived components as much as possible. |
| priorityDate | 2001-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 304.