| abstract |
The following general formula (1) [In the formula, R 1 and R 2 each represent a hydrogen atom or a methoxy group. When R 2 is a hydrogen atom, R 1 is a methoxy group. When R 2 is a methoxy group, R 1 is a hydrogen atom. A represents an oxygen atom, a sulfur atom, CH = CH, CH = N or NR 3 (where R 3 is a hydrogen atom, a lower alkyl group, a hydroxy lower alkyl group, a lower alkoxy lower alkyl group, an aryl group or B represents a nitrogen atom, CH or CR 4 (where R 4 is a hydrogen atom, a lower alkyl group, a hydroxy lower alkyl group, a lower alkoxy lower alkyl group, an aryl group or an aryl lower alkyl group) M represents a number of 1 or 2; n represents a number of 1 to 5] And an acid addition salt thereof or a hydrate thereof; and a medicament containing the same. It has a cell adhesion inhibitory effect and is useful as a medicine for allergy, asthma, rheumatism, arteriosclerosis, inflammation and the like. |