| abstract |
Equation (1) [In the formula, 1 to 4 R 1 -X- are the same or different. Ring A is a saturated or unsaturated 5-membered heterocyclic ring, X represents a single bond or a group represented by the formula: —N (R 3 ) —, —O—, or —S—, R 1 represents a hydrogen atom, a halogen atom, a nitro group, a carboxyl group, a substituted or unsubstituted alkyl group, or the like; R 2 represents a hydrogen atom, a halogen atom, a nitro group, a carboxyl group, a substituted or unsubstituted alkyl group, R 3 represents a hydrogen atom, a substituted or unsubstituted alkyl group, or the like. Or a prodrug thereof or a pharmaceutically acceptable salt thereof is a compound useful as a therapeutic agent for a disease associated with Rho kinase. |