| abstract |
The present invention provides a drug containing a novel carboxylic acid derivative useful as an insulin sensitizer as an active ingredient. Specifically, the present invention provides a carboxylic acid derivative represented by the following general formula (I), a salt thereof, an ester thereof, or a hydrate thereof. In the formula, R 1 is a carboxyl group, an alkyl group, an alkoxy group, etc .; L and T are a single bond, an alkylene group, an alkynylene group, etc .; M is an alkylene group, W is a carboxyl group; X is an oxygen atom; NR X1 CQ 1 O -, - OCQ 1 NR X1 -, - CQ 1 NR X1 O- ( and wherein Q 1 represents an oxygen atom, R X1 represents a hydrogen atom, an alkyl group, respectively) and the like; Y, Z represents a 5- to 14-membered aromatic group which may have a substituent or the like. |