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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-351
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filingDate 2002-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2004-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-WO2002066464-A1
titleOfInvention β-lactam compound, method for producing the same, and serum cholesterol lowering agent containing the same
abstract It is a novel β-lactam compound represented by the following general formula (I). Useful as a serum cholesterol lowering agent. [Wherein A 1 , A 3 and A 4 are a hydrogen atom, a halogen, a C 1 -C 5 alkyl group, a C 1 -C 5 alkoxy group, -COOR 1 , the following formula (b): (In the formula, R 1 is a hydrogen atom or a C 1 -C 5 alkyl group.) Or a group represented by the following formula (a): [Wherein, R 2 represents a —CH 2 OH group, —CH 2 OC (O) —R 1 group or —CO 2 —R 1 group, R 3 represents a —OH group or —OC (O) —R 1 group, R 4 is — (CH 2 ) k R 5 (CH 2 ) 1 — (where k and l are 0 or an integer of 1 or more, and k + 1 is an integer of 10 or less), and R 5 is a bond. It represents a single bond, -CH = CH -, - OCH 2 -, carbonyl group or -CH (OH) -. And any one of A 1 , A 3 and A 4 is always a group represented by the above formula (a). A 2 is a C 1 -C 5 alkyl chain, a C 1 -C 5 alkoxy chain, a C 1 -C 5 alkenyl chain, a C 1 -C 5 hydroxyalkyl chain or a C 1 -C 5 carbonylalkyl chain. It is. n, p, q and r represent an integer of 0, 1 or 2. ] Or a pharmaceutically acceptable salt thereof.
priorityDate 2001-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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