http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2002064768-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 |
| filingDate | 2001-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2002064768-A1 |
| titleOfInvention | Screening method of inhibitor for bacterial chromosome segregation function and inhibitor obtained by the screening method |
| abstract | The present invention relates to a plasmid in which a chromosome partitioning protein mukB gene on a bacterial chromosome is integrated with a fusion gene obtained by binding a fluorescent marker gene downstream of the mukB gene, a drug resistance gene, and a temperature-sensitive mutant gene encoding a replication initiation protein. A test substance is brought into contact with the host cell in which the homologous recombination gene has been replaced, and the presence or absence of the formation of a fluorescent focus is observed. Thus, a MukFEB complex composed of MukF, MukE and MukB proteins responsible for the main function of chromosome segregation is obtained. The purpose of the present invention is to provide a simple and rapid method for searching for a novel and useful antibacterial agent, which screens for substances that inhibit body formation. It is extremely useful as an antibacterial agent based on a novel mechanism of action. |
| priorityDate | 2001-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.