abstract |
INDUSTRIAL APPLICABILITY The present invention is useful as an agent for preventing or treating diseases caused by hyperglycemia, such as diabetes, diabetic complications, and obesity, which have improved oral absorption and exhibit excellent human SGLT2 activity inhibitory action in vivo. A general formula (P is a hydrogen atom or a group constituting a prodrug, R 1 is a hydrogen atom, a substitutable amino group, a carbamoyl group, a substitutable lower alkyl group, a substitutable lower alkoxy group, or the like; R 2 is a hydrogen atom or lower alkyl group; R 3 is a substituted or lower alkyl group, a substituted or lower alkoxy group, a substituted or lower alkylthio group, etc.), a glucopyranosyloxybenzylbenzene derivative, a pharmaceutically acceptable salt thereof, and a pharmaceutical use thereof. To provide. |