| abstract |
The present invention provides a compound represented by the general formula [I]: [Wherein, A 1 and A 2 represent a methine group or the like which may be substituted with a fluorine atom, B represents a halogen, a cyano group, a lower alkyl group, or the like, and D has a substituent. And G represents an aliphatic group having 3 to 20 carbon atoms such as an aliphatic cyclic group. And the like. This compound inhibits the action of nociceptin by having a high affinity for the nociceptin receptor, and is an analgesic, an antiobesity agent, a brain function improving agent, a drug for treating Alzheimer's disease, a drug for treating dementia, a drug for treating schizophrenia It is useful as a remedy for degenerative neurodegenerative diseases, an antidepressant, a drug for diabetes insipidus, a drug for polyuria, a drug for hypotension, and the like. |