| abstract |
The differential display method was used to search for genes with differential expression in eosinophils collected during the exacerbation and remission periods of patients with atopic dermatitis. As a result, genes “2259-01”, “2298-09”, “2255-02”, “2292-04”, and “2182” whose expression is significantly increased in eosinophils of patients in remission are significantly increased. -02 "was isolated. The present inventors have found that these genes can be used for testing for allergic diseases and for screening therapeutic drug candidate compounds. |