abstract |
An effective therapeutic agent for ischemic disease containing human granulocyte colony stimulating factor (human G-CSF) as an active ingredient is disclosed. By administering this therapeutic agent, it is possible to eliminate the drawbacks of conventional exercise therapy, pharmacotherapy, revascularization, and recently proposed gene therapy and intramuscular transplantation of bone marrow cells, especially for atherosclerosis obliterans. New treatments are provided. Further, the present therapeutic agent can be a therapeutic agent for ischemic diseases such as ischemic cerebrovascular disease and ischemic heart disease. |