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filingDate 2001-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2004-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-WO2002018322-A1
titleOfInvention Method for producing benzoic acid derivative crystals
abstract 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl) carbamoyl] benzoic acid crystal having a single endothermic peak at around 233 ° C. in differential scanning calorimetry Wherein the crystal of 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl) carbamoyl] benzoic acid is treated with a mixture of water and ethanol. A method comprising the step of recrystallizing. A type II crystal that is stable against physical impact can be selectively produced, and the obtained crystal does not contain highly toxic hexane as a residual solvent, and thus can be suitably used as an active ingredient of a drug. .
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